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It was discovered that naltrexone and bupropion combined, that could be marketed later on as Contrave, provide better weight loss results than eating and working out alone.

Using two separate drugs to lose weight naturally can be very effective you will find combinations as you're watching FDA now awaiting approval. When dealing with weight reduction and the people that go through it you need to err on the side of caution and allow FDA do its job and demand some research be done in order that the public recognizes the side effects and hazards of the medications before we take them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on his or her medications.

Researchers found out that participants investing in this drug for a year, dropped excess weight within four weeks and have kept the body weight off during the entire 56 weeks of the study. Contrave is often a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs that are made up of more than one active ingredient, which might make them far better and safer.

Combo-pilling could be the newest fad or also the newest to come under scrutiny and so it is just more publicly known recently, comb-pilling for weight reduction has been around since the eighties. The biggest reason that utilizing a combination of pills is becoming popular will be the fact that since right now there are not any long term prescription slimming capsules that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and shouldn't be taken in individuals with seizure disorders. The drug could also raise blood pressure and heartrate, and must not be used in individuals with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure and heartbeat and must not used in patients with uncontrolled high blood pressure, in addition to by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes with a boxed warning to alert health care professionals and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.


New UCLA study on smokers with mental, drug, and alcohol problems
Status
Pending